Optimisation of flagging around new white blood cell precursor channel

• Research type

  Research Study

• Full title

  Optimisation of flagging primarily around new white blood cell precursor channel (WPC) mode on Sysmex XN-20 to reduce morphological examination.

• IRAS ID

  250249

• Contact name

  Laura Ahmed

• Contact email

  L.Ahmed@mmu.ac.uk

• Sponsor organisation

  Manchester University NHS Foundation Trust

• Duration of Study in the UK

  0 years, 4 months, 31 days

• Research summary

  This project is based on the flagging performance of the Sysmex XN-20 analyser, which works by doing a reflex test on samples that have flagged up for blasts/abnormal lymphocytes on the Sysmex XN-10 analyser. The XN-20 uses the White cell precursor channel to separate the flags that are produced on XN-10 into blast cells or abnormal lymphocytes. The samples are also examined under the microscope to know if the blast cells or abnormal lymphocytes flags are true positive or false positive. At the end of this project, it is hoped that there will be reduction in the amount of blood film examinations being done in the laboratory at Manchester Foundation Trust (MFT).

• REC name

  North West - Greater Manchester South Research Ethics Committee

• REC reference

  19/NW/0064

• Date of REC Opinion

  28 Feb 2019

• REC opinion

  Favourable Opinion