OPPORTUNITY
Research type
Research Study
Full title
Osteoarthritis Preoperative Package for care of Orthotics, Rehabilitation, Topical and oral agent Usage and Nutrition to Improve ouTcomes at a Year (OPPORTUNITY)
IRAS ID
234415
Contact name
Hamish Simpson
Contact email
Duration of Study in the UK
1 years, 2 months, 31 days
Research summary
Osteoarthritis (OA) is the fastest growing cause of disability worldwide. Patients with severe OA are referred to secondary care for consideration of joint replacement surgery. Patients’ pre-operative health and physical function is known to influence their postoperative outcomes and non-operative treatments such as exercise, shoe insoles, painkillers and weight loss are known to benefit patients with OA however these options are often not optimised prior to joint replacement.
The OPPORTUNITY study is a multicentre randomised controlled feasibility trial which aims to assess the feasibility and acceptability of a pre-operative package of non-operative care versus standard care prior to joint replacement.
The intervention is composed of four elements and patients will be provided with whichever elements of the package they qualify for; a weight loss programme, footwear review, painkiller review and exercises to do at home. The patient group will be patients that have been recently placed on the waiting list for a total knee replacement due to osteoarthritis. The study aims to take advantage of the incentive for behavioural change in these patients to obtain a durable alteration in the patients’ weight and exercise level, which coupled with appropriate analgesia and insoles could relieve the morbidity of their OA and improve outcomes following surgery. Participants will be asked to undertake the intervention for 8-12 weeks, depending on when they are scheduled for surgery. All participants will attend for study visits at baseline, end of intervention (pre-surgery) and 3 months after planned surgery date. Participants will also be invited to take part in an interview with a researcher to discuss the intervention. Health care practitioners involved in the delivery of the intervention will be invited for interview as well as staff at the sites where the intervention is being delivered.
REC name
South East Scotland REC 02
REC reference
17/SS/0156
Date of REC Opinion
15 Dec 2017
REC opinion
Favourable Opinion