Open Corona Research Platform - Phase I [COVID-19]
Research type
Research Study
Full title
Open Coronavirus Research Platform - Phase I: Retrospective analyses of healthcare records for patients hospitalised with COVID-19.
IRAS ID
282148
Contact name
Ben Goldacre
Contact email
Sponsor organisation
NHS England
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
We are conducting urgent observational research on Covid-19 using very large existing primary care electronic health record datasets (for >20 million patients in England) linked to intensive care records, Covid-19 lab data and mortality. We are rapidly building a secure, collaborative analytics platform for approved users. Initially this will contain key datasets: GP data on NHS patients managed by the EHR provider TPP (who cover 40% of practices in the country); and outcomes data matched on from the new NHS England and NHSX data store (CPNS deaths data; ICNARC ITU admissions data; ECDS A&E patient-level data; ONS deaths data; all pseudonymised). This big data approach is necessary to get sufficient statistical power to detect associations with specific medications and medical conditions as early as possible during the pandemic and thereby save lives by modifying patient, clinician, and population behaviour. We are working in collaboration with NHS England, who are acting as Data Controller for the purposes of this urgent project. Our DPIA approving data flows and access to these datasets has already been signed by the DPO at NHS England. \n\n[Study relying on COPI notice]
REC name
London - City & East Research Ethics Committee
REC reference
20/LO/0651
Date of REC Opinion
6 Apr 2020
REC opinion
Favourable Opinion