North West Paediatric Neurosurgery Network AVM outcomes
Research type
Research Study
Full title
The longterm follow up of neurosurgical patients with arteriovenous malformations in the North West Paediatric Neurosurgery Network
IRAS ID
203141
Contact name
Conor Mallucci
Contact email
Sponsor organisation
NHS Alder Hey Children's Hospital
Duration of Study in the UK
0 years, 3 months, 1 days
Research summary
Arteriovenous malformations are abnormal connections between the high pressure arterial blood vessels and the normally low pressure venous blood vessels. The can occur anywhere in the body but within the brain they can pose a particularly serious risk.\n\nBrain AVMs are normally discovered after a bleed or because of seizures or headache. Within the paediatric population, although the condition is rare, there is a higher rate of presentation with bleeding.\n\nNeurosurgeons have three main modalities for treating brain AVMs; microsurgical resection(surgical removal of the lesions), endovascular embolization (blocking the abnormal blood vessels feeding the AVM)and stereotactic radiosurgery (using radiation to obliterate the lesion). The treatment that is used if dependent on the location of the AVM within the brain and the clinical condition of the patient.\n\nWe will study the outcomes of children in the North West Paediatric Neurosurgery service using two validated questionnaires. We wish to measure the functional outcomes for these children, any disabilities they may now by dealing with and also if there is an association of a particular activity (exercise/sport) with bleeding events.\n
REC name
North West - Greater Manchester West Research Ethics Committee
REC reference
17/NW/0294
Date of REC Opinion
16 Jun 2017
REC opinion
Further Information Favourable Opinion