Non-luer one way filter valve intravenous needle and the blood patch
Research type
Research Study
Full title
Serum blood clotting changes during blood sampling via non-luer one-way filter valve intravenous needle: Implication on the epidural blood patch procedure
IRAS ID
196031
Contact name
Paul Sharpe
Contact email
Sponsor organisation
NHS Organisation
Duration of Study in the UK
0 years, 6 months, 1 days
Research summary
Patient safety agencies such as National Patient Safety Agency (NPSA) and European Medicines Agency recommend adoption of equipment that prevents wrong route drug administration. For example, medicine intended for the intravenous route should not be possible to be given via the epidural route, hence limiting potentially catastrophic complications associated with human error. However, the epidural blood patch requires equipment that connects to the intravenous and epidural route as blood is taken from a patient and then it is injected into the patients’ epidural space for therapeutic affect. Hence equipment is required that allows blood aspiration from the patient but does not have the potential to inject into the patient to comply with patient safety agency recommendations.
This research aims to determine if aspirating blood from the patient via the non-leur one-way filter valve needle has the potential of activating the clotting cascade. If this occurred it could reduce the time the clinician has to utilise the blood before it clots in the syringe and this also has unknown implications on the therapeutic affect of the epidural blood patch.
The epidural blood patch is mainly used in obstetric anaesthesia in the treatment of dural puncture headaches however it is also used to treat conditions such as spontaneous intracranial hypotension, hence this study involves pregnant and non-pregnant populations.
REC name
North West - Greater Manchester South Research Ethics Committee
REC reference
16/NW/0570
Date of REC Opinion
28 Jul 2016
REC opinion
Favourable Opinion