Non-invasive MRI for portal hypertension

• Research type

  Research Study

• Full title

  Multi-site validation of non-invasive MRI measures of portal hypertension

• IRAS ID

  258140

• Contact name

  Jonathan A Fallowfield

• Contact email

  Jonathan.Fallowfield@ed.ac.uk

• Duration of Study in the UK

  0 years, 5 months, 0 days

• Research summary

  The complications from chronic liver disease result mainly from raised pressures within the liver. We currently measure this pressure by passing a long catheter through the jugular vein in the neck into the liver. This is an expensive and invasive test which is not available outside specialised liver centres. In Nottingham, researchers have developed a new technique which provides a surrogate measure of pressure non-invasively using Magnetic Resonance Imaging.
  The aim of this study is to show multicentre validity of non-invasive MRI measures of assessing the severity of portal hypertension, which can be used to develop tools to effectively stratify patients with regards to treatment and long term-outcomes.

• REC name

  West of Scotland REC 5

• REC reference

  19/WS/0050

• Date of REC Opinion

  1 Apr 2019

• REC opinion

  Further Information Favourable Opinion