NIMBLE

• Research type

  Research Study

• Full title

  Nodule Immunophenotyping Biomarker for Lung Cancer Early Diagnosis Study

• IRAS ID

  288433

• Contact name

  Richard Lee

• Contact email

  richard.lee@rmh.nhs.uk

• Sponsor organisation

  The Royal Marsden NHS Foundation Trust

• Duration of Study in the UK

  10 years, 0 months, 1 days

• Research summary

  Incidental lung nodules are common, and may represent early cancers. Their assessment can result in delayed diagnosis while interval imaging is performed to assess risk.

  This study will allow us to examine the potential for imaging and blood biomarkers to augment nodule stratification, identifying high-risk patients who may benefit from more frequent surveillance or earlier diagnostic procedures, and low risk patients suitable for reduced surveillance intensity. This is particularly relevant for the COVID-19 era to stratify hospital attendances and high risk interventions to those in greatest need. This project dovetails with existing radiomics and lung biomarker research (LIBRA and Lung Health Check Biomarker Study) within our early diagnosis research group.

• REC name

  London - Brighton & Sussex Research Ethics Committee

• REC reference

  21/LO/0138

• Date of REC Opinion

  1 Apr 2021

• REC opinion

  Further Information Favourable Opinion