New Methods of Detecting Problems in Pregnancy - Sample Bank

• Research type

  Research Tissue Bank

• IRAS ID

  155633

• Research summary

  New Methods of Detecting Problems in Pregnancy - Sample Bank

• REC name

  South Central - Oxford C Research Ethics Committee

• REC reference

  14/SC/1020

• Date of REC Opinion

  8 Jul 2014

• REC opinion

  Further Information Favourable Opinion

• Data collection arrangements

  The samples will be stored in The Clatterbridge Cancer Centre (CCC) Research Laboratrory. There is restricted
  access to the laboratory controlled by electronic swipe. The samples will be stored in a 86C freezer which is for the storage ofthe CCC Biobank samples only.
  We will collect and store the following samples following informed consent:
  1. Anticoagulated blood for the preparation and storage of plasma, buffy coat and cellular material
  2. Coagulated blood for the preparation and storage of serum
  3. Urine
  4. Saliva
  5. Ascites fluid
  A medically qualified clinician will request consent for the samples and clinical data to be used for research. The
  aims of the biobank will be explained to the participant and they will be given an information sheet and time to consider
  whether to consent. The participant will be given the opportunity to ask any questions and fully discuss the
  implications of gifting samples to the biobank. The clinician will then receive informed consent for the samples to be
  taken. The samples will be collected processed and stored according to Standard Operating Procedures.

• Research programme

  The Clatterbridge Cancer Centre (CCC) has a welldefined mission to ‘improve health and wellbeing through compassionate, safe and effective cancer care’. Research for patient benefit is a fundamental part of CCC; the aim is to conduct high quality research which translates into improved treatment and better prognosis for our patients. The establishment of a CCC Biobank aims to provide high quality biological samples linked to patient outcome data to facilitate good quality research into the molecular mechanisms of cancer, biomarker discovery for early detection of cancer, patient stratification and into the reasons why some cohorts of patients fail to respond to therapeutic agents; all of which it is hoped will result in tangible patient benefit. The sample collection is entirely prospective following full informed consent from CCC patients diagnosed with cancer. The Biobank will also store samples donated from ‘healthy volunteers’ who have not been diagnosed with cancer in order to provide age matched controls. The biobank aims to support the cancer research agenda and contribute to high quality scientific cancer research.

• RTBTitle

  New Methods of Detecting Problems in Pregnancy - Sample Bank

• Establishment organisation

  North East Thames Regional Genetics Service

• Establishment organisation address

  Great Ormond Street Hospital NHS Foundation Trust

  Level 5, York House

  37 Queen Square, London

  WC1N 3BH