Natural killer cell receptors

  • Research type

    Research Study

  • Full title

    Natural killer cell receptors

  • IRAS ID

    206084

  • Contact name

    David Adams

  • Contact email

    da1@sanger.ac.uk

  • Sponsor organisation

    Genome Research Ltd

  • Duration of Study in the UK

    2 years, 1 months, 20 days

  • Research summary

    We are a team of researchers at the Wellcome Sanger Institute and have been funded from Open Targets (a consortium of Biogen, Celgene, EMBL-EBI, GlaxoSmithKline, Takeda, and the Wellcome Sanger Institute, http://opentargets.org/about). We are trying to find new interactions between cancer cells and the immune system, focussing on Natural Killer (NK) cells. We aim to identify new interactions using in vitro assays and then understand the functional importance using NK cells isolated from peripheral blood and determining how well they kill a range of cancer cells which express differing levels of these newly identified interactors. This functional information will be used to investigate the role of these proteins in cancer biology and develop new therapies

  • REC name

    Yorkshire & The Humber - Leeds West Research Ethics Committee

  • REC reference

    18/YH/0301

  • Date of REC Opinion

    30 Jul 2018

  • REC opinion

    Favourable Opinion