Naso-ethmoidal EEG recording - A pilot study
Research type
Research Study
Full title
Naso-ethmoidal EEG recording - A pilot study
IRAS ID
225526
Contact name
Dora Lozsadi
Contact email
Sponsor organisation
St. George's University of London
Duration of Study in the UK
1 years, 1 months, 1 days
Research summary
Electroencephalography recordings (EEG) are a useful tool in the evaluation of patients suffering epilepsy. Focal seizures generated in central areas of the brain are difficult to assess using routine scalp electrodes distant from these sites. This may lead to incorrectly negative routine EEGs. Recording close to abnormal brain region increases the diagnostic yield but currently involves surgery.
Ear-nose-throat, EEG and epilepsy specialists at St George’s Hospital plan a pilot study to assess a new minimally invasive technique to monitor brain activity using electrodes inserted into the nose. This low-risk method is expected to provide useful and reliable information about patients suffering epilepsy generated behind and/or above the nose, reducing the number of incorrect diagnoses, seizure classification and avoiding additional invasive tests.
If results are positive, nasal electrodes have the potential for immediate application. Groups benefiting are patients suffering frontal lobe seizures, potentially ambulatory monitoring, development of discrete and reliable seizure alarms, to name a few. Nasal electrodes may be included in the standard protocols for EEG video telemetry after further evaluation.
REC name
London - West London & GTAC Research Ethics Committee
REC reference
17/LO/0842
Date of REC Opinion
23 Aug 2017
REC opinion
Further Information Favourable Opinion