MYOPROSP
Research type
Research Study
Full title
A prospective cohort study to identify a stratified approach in the diagnosis, treatment and delivery of care in adult idiopathic inflammatory myopathy (MYOPROSP)
IRAS ID
164257
Contact name
Hector Chinoy
Contact email
Duration of Study in the UK
4 years, 11 months, 27 days
Research summary
Idiopathic Inflammatory Myopathies (IIM), also know as myositis, is a rare condition that causes inflammation of the muscles and can result in weakness, fatigue and disability. It can also affect other parts of the body including the skin, joints, heart, lungs and digestive tract. Treatment involves the suppression of inflammation using anti inflammatory medication before permanent damage results. However, the outcome for patients with myositis is not as good as it could be and needs to be improved. For this reason we are planning a research study to find better ways to diagnose, treat and improve the care of patients with myositis.
Patients wishing to take part will ideally attend for 4 study visits over the course of 12 months. If they continue to be seen at the hospital, they may also be asked to provide further blood samples and information on an annual basis for 5 years. At the initial visit they will be asked to sign a consent form, give a blood sample, undergo a clinical assessment and complete a number of questionnaires. Additionally (as part of their routine clinical care), they will be asked to undertake an MR scan of their muscle, a muscle biopsy, and be given the option of an MR contrast scan of their heart (these clinical results will be used as part of research findings. Follow up visits at 3, 6 and 12 months will involve further blood samples, clinical assessments and questionnaires. Additionally, they will be given the option of a second MR muscle scan, a repeat muscle biopsy and an MR contrast scan of their heart at the 6 month follow up visit.It is hoped that the information gained from this study will help identify better ways to diagnose, treat and improve the care of patients with myositis.
REC name
North East - York Research Ethics Committee
REC reference
15/NE/0104
Date of REC Opinion
27 Mar 2015
REC opinion
Further Information Favourable Opinion