MULTIPLE

  • Research type

    Research Study

  • Full title

    Multiple Long-term Conditions Registry UK pilot (MULTIPLE)

  • IRAS ID

    310536

  • Contact name

    Miles Witham

  • Contact email

    miles.witham@nhs.net

  • Sponsor organisation

    Newcastle Hospitals NHS Foundation Trust

  • Duration of Study in the UK

    0 years, 11 months, 28 days

  • Research summary

    This project establish a UK wide registry of people with multiple long-term conditions interested in taking part in research, with a minimum data set to enable us to match people to future studies. We will maximise the flexibility of recruitment methods to ensure that recruitment is as inclusive as possible in line with the recent INCLUDE guidance from NIHR.

    We will enrol 500 participants from 10 UK centres (4 in North East England, the other 6 spread across the UK). People aged 40 and over with 4 or more long-term conditions (from a standard list of 43 conditions) will be eligible. Recruitment will be conducted via response to direct advertising, by approach to potentially eligible participants through mailshots from primary care, and through approaching patients in hospital outpatient clinics.

    Participants will be able to join the study for face to face consent and assessment or for telephone/postal consent and assessment. After consent is obtained, information from GP and hospital records will be linked to participants baseline study information. For participants choosing face to face assessment, measures of physical fitness (grip strength and short physical performance battery) will be obtained at a one-off study visit. For all participants, information on memory, depression, quality of life, age, sex, ethnicity, location and medications will be collected. All participants will be asked for permission to be recontacted for future studies and only those who agree to be recontacted will be included in the registry.

  • REC name

    North East - Newcastle & North Tyneside 2 Research Ethics Committee

  • REC reference

    22/NE/0014

  • Date of REC Opinion

    27 May 2022

  • REC opinion

    Further Information Favourable Opinion