Mucosal Immune Responses to COVID-19 [COVID-19]
Research type
Research Study
Full title
An investigation of quality and longevity of mucosal immune responses to SARS-CoV-2 infection.
IRAS ID
287928
Contact name
Julian K-C. Ma
Contact email
Sponsor organisation
St George's University of London
Duration of Study in the UK
1 years, 6 months, 0 days
Research summary
COVID-19 is a serious infection that affects the respiratory system and other mucosal areas of the body. Mucosal tissues are those parts of your body which are inside your body, but exposed to the environment – such as the mouth, nose, respiratory and gastrointestinal systems.
These mucosal tissues are protected by your general immune system, but also have their own specialised immune mechanisms which are inter-linked. So, an infection in your lungs or gut can result in localised immunity in your mouth or nose.
The purpose of this sample study is to investigate the role and importance of this special mucosal immunity in responding to COVID-19. Samples will be taken from volunteers who have either had or not had COVID-19. In some cases, repeat samples will be collected so that we can study mucosal immunity over time. The results will provide valuable information about natural immunity to COVID-19 and provide a guide to what types of immunity we need to aim for, from a COVID-19 vaccine.REC name
East Midlands - Nottingham 1 Research Ethics Committee
REC reference
20/EM/0227
Date of REC Opinion
10 Sep 2020
REC opinion
Favourable Opinion