MRI for lung cancer radiotherapy

  • Research type

    Research Study

  • Full title

    Using lung ventilation imaging to optimise lung cancer radiotherapy plans

  • IRAS ID

    330496

  • Contact name

    Rachel A Pearson

  • Contact email

    rachel.pearson1@nhs.net

  • Sponsor organisation

    The Newcastle upon Tyne Hospitals NHS Foundation Trust

  • Duration of Study in the UK

    0 years, 8 months, 13 days

  • Research summary

    Radiotherapy treatment of lung cancer aims to destroy tumour
    and prevent recurrence, whilst limiting radiation exposure to non-tumour regions. Many lung
    cancer patients have other lung disease that result in heterogeneous function, and lung function
    can worsen in some after radiotherapy as the treatment damages the few remaining lung regions
    with good function. We have developed 3D MRI scan measurements of lung function, we will test
    their ability to report on lung functional heterogeneity in lung cancer patients and test the ability
    to use this functional information to produce better radiotherapy treatment strategies that limit
    radiation impact on post-treatment lung function.

  • REC name

    London - City & East Research Ethics Committee

  • REC reference

    23/PR/1087

  • Date of REC Opinion

    6 Oct 2023

  • REC opinion

    Favourable Opinion