MRI for lung cancer radiotherapy
Research type
Research Study
Full title
Using lung ventilation imaging to optimise lung cancer radiotherapy plans
IRAS ID
330496
Contact name
Rachel A Pearson
Contact email
Sponsor organisation
The Newcastle upon Tyne Hospitals NHS Foundation Trust
Duration of Study in the UK
0 years, 8 months, 13 days
Research summary
Radiotherapy treatment of lung cancer aims to destroy tumour
and prevent recurrence, whilst limiting radiation exposure to non-tumour regions. Many lung
cancer patients have other lung disease that result in heterogeneous function, and lung function
can worsen in some after radiotherapy as the treatment damages the few remaining lung regions
with good function. We have developed 3D MRI scan measurements of lung function, we will test
their ability to report on lung functional heterogeneity in lung cancer patients and test the ability
to use this functional information to produce better radiotherapy treatment strategies that limit
radiation impact on post-treatment lung function.REC name
London - City & East Research Ethics Committee
REC reference
23/PR/1087
Date of REC Opinion
6 Oct 2023
REC opinion
Favourable Opinion