MRI catheterization for congenital heart disease (v 1.0)
Research type
Research Study
Full title
Diagnostic cardiac catheterization for congenital heart diseases under MR guidance
IRAS ID
184807
Contact name
Reza Razavi
Contact email
Sponsor organisation
King's College London
Duration of Study in the UK
1 years, 8 months, 1 days
Research summary
Diagnostic cardiac catheterizations are a common procedure used in children and adults with congenital heart disease to assess the state of the circulation, feasibility for surgical repair and to plan future interventional and pharmacological treatment. Although giving a wealth of information, diagnostic cardiac catheterizations implicate exposure to x-rays, which involve radiation that can have long-term effects on patients and medical personnel.
An MRI (magnetic resonance imaging) catheterization involves having an MRI scan combined with a cardiac catheter. These two procedures are performed together because they provide complimentary information. In a first stage, a cardiac catheterization is carried out under MRI guidance and if not successfully completed then under x-ray guidance; we use the catheters to measure the pressures in the different heart chambers. After the catheter is positioned in the correct place, we move the patient into the MRI scanner (or x-ray if necessary) so we can measure the pressures of the heart chambers using the catheters in addition to measuring other parameters using the MRI scanner.
Due to recent advances in MRI technology, we are able to guide cardiac catheters using MRI. In this study, we will use a research tool connected to the MRI scanner called iSuite that allows visualization of catheter in the anatomical context to guide the catheterization. This would facilitate the visualisation of the catheter, decreasing the need for X-ray in this kind of procedures. The wire we use to help with this guidance would be non-metallic. Both the catheter and the wire are standard CE-marked products.
The performance of the catheterization under MRI guidance provides doctors with better information of the heart of the patient. Using the iSuite software would improve the visualisation of the catheters under MRI therefore reducing or even avoiding radiation completely.REC name
London - Bloomsbury Research Ethics Committee
REC reference
16/LO/0173
Date of REC Opinion
22 Mar 2016
REC opinion
Further Information Favourable Opinion