MOVE MI and glycemia
Research type
Research Study
Full title
Effects of reducing and breaking up sitting time with standing and light intensity activity in free-living conditions on glycemia post myocardial infarction.
IRAS ID
296029
Contact name
Joanna Richards
Contact email
Sponsor organisation
University of Bedfordshire
Duration of Study in the UK
1 years, 0 months, 0 days
Research summary
Cardiovascular Disease (CVD) is one of the greatest causes of mortality and morbidity globally, particularly in middle to high income countries. In the UK alone, it was accountable for 124,641 deaths in 2017. Further to this, CVD contributes to a vast economic burden, costing the National Health Service (NHS) £19billion annually. This is mainly due to a significant number of hospital readmissions following a first cardiac event (198,000 per annum).
Following a cardiac event, an individual is therefore recommended to reduce their risk factors, including lipid profile, smoking status and physical inactivity, to reduce their risk of a secondary event. In healthy individuals, regularly breaking up sitting time reduces cardiometabolic risk markers by measuring continuous glucose levels and blood pressure. The aim of this study is to therefore observe if this effect is replicated in the cardiac population and thus whether breaking up sitting time will reduce the risk of a secondary cardiac event.
Potential participants will be required to meet an inclusion criteria to take part in the study: aged 50 years or above and had a myocardial infarction within the past three months at the time of recruitment to the study.A repeated measures, randomised cross over study design will be used. All data collection will take place either at the Sport Science laboratories at University of Bedfordshire, or remotely, at the participant’s home or workplace with social distancing in place, dependant on the individual's preference and current Government guidance around COVID-19 at that time. This will ensure we are working with current COVID-19 guidelines, to allow safe data collection. Participants will complete four days of each experimental condition in a random counterbalanced order: 1) uninterrupted sitting; 2) sitting interrupted with standing or light intensity physical activity breaks.
REC name
East Midlands - Nottingham 2 Research Ethics Committee
REC reference
21/EM/0101
Date of REC Opinion
4 May 2021
REC opinion
Favourable Opinion