Mould and mycoprotein sensitisation

  • Research type

    Research Study

  • Full title

    Evaluation of the relationship between sensitisation to mould/ fungi and mycoprotein: a case-control study

  • IRAS ID

    289240

  • Contact name

    Stephen Till

  • Contact email

    stephen.till@kcl.ac.uk

  • Sponsor organisation

    King's College London

  • Duration of Study in the UK

    0 years, 11 months, 30 days

  • Research summary

    Mycoprotein is the main ingredient of Quorn food products and is produced via fermentation of the fungus Fusarium venenatum. Allergic reactions to mycoprotein have been recorded but are thought to be very uncommon. Given that mycoprotein is derived from fungus, it has been hypothesized that there could be a link between allergies to airborne fungi/mould and allergy to ingested quorn. However this has never been formally investigated. The aim of this study is therefore to investigate if people who are allergic to mould are likely to also be allergic to mycoprotein.

    This study will take place at Guy's Hospital in adults. Firstly, adults with a known history of allergic reactions to mycoprotein will be recruited. They will undergo skin prick testing and blood sampling to validate the tests for mycoprotein allergy. Secondly, participants with and without sensitisation to moulds will be recruited and will undergo skin prick testing and blood sampling. The results will then be compared.

  • REC name

    South Central - Hampshire B Research Ethics Committee

  • REC reference

    21/SC/0278

  • Date of REC Opinion

    16 Nov 2021

  • REC opinion

    Further Information Favourable Opinion