MORE2 v1.0
Research type
Research Study
Full title
MACROPHAGE FOR REGENERATIVE MEDICINE IN CIRRHOTICS – II
IRAS ID
229265
Contact name
Stuart Forbes
Contact email
Sponsor organisation
University of Edinburgh
Clinicaltrials.gov Identifier
N/A, N/A
Duration of Study in the UK
1 years, 4 months, 27 days
Research summary
Cirrhosis of the liver is the end process of continuous injury to the organ by any cause. There is currently no treatment beside liver transplant for cirrhosis. Prof Forbes group has worked for years on the development of cellular therapy to cure cirrhosis.
This study is looking to improve a currently used method to produce cellular therapy for patients with cirrhosis of the liver. We are running a parallel study (MATCH) to compare this cellular therapy in cirrhotic patients against standard of care. The Blood Transfusion team and the scientists at the University of Edinburgh are looking to make the production process more streamlined allowing larger scale production and reducing production time. This will be a step towards widespread production of a potentially curative therapy for cirrhosis of the liver and also will allow the opening of the MATCH trial multicentre across UK.REC name
West of Scotland REC 5
REC reference
19/WS/0006
Date of REC Opinion
18 Jan 2019
REC opinion
Favourable Opinion