MOPED
Research type
Research Study
Full title
Management and Outcomes of Perioperative Care among European Diabetic Patients: (MOPED): A prospective observational, international cohort study
IRAS ID
306741
Contact name
Simon Howell
Contact email
Sponsor organisation
University of Leeds
Clinicaltrials.gov Identifier
NCT04511312, Trials Registration Number; 1/378/2167, IRB Mater Misericordiae University Hospital
Duration of Study in the UK
2 years, 6 months, 1 days
Research summary
Diabetes is common in people undergoing surgery. Patients with diabetes who have surgery may be at higher risk of problems following surgery when compared to the general population. The management of patients with diabetes undergoing surgery varies significantly across hospitals and countries with important differences in national guidelines. We will explore variation in the way diabetes is managed during the time around surgery. We will study how the outcomes from surgery are linked with how well controlled the patient's diabetes is before the operation. We will ask patients who have diabetes and who are having surgery (both planned and emergency) to take part. Some minor procedures (for example, only needing local anaesthetic) will be excluded. All patients who give informed consent will receive normal care. This study will gather information about the current management of diabetes before, during and after surgery. The main outcome in this study is the number of days spent at home in the 30 days after surgery. We will also collect information about any complications of surgery and anaesthesia. We will assess the recovery of patients using a short questionnaire (QOR-15). The aim of this research is to improve the care of patients with diabetes undergoing surgery by understanding how care is currently given and examining associations between different strategies and outcomes following surgery. We will use the information from this study to inform an improvement science based approach to improving the care and outcomes of patients with diabetes undergoing surgery. This study has infrastructure support from the European Society of Anaesthesiology Clinical Trial Network (ESA-CTN). It will look at 5,000 adult patients from at least 50 different hospitals in at least 10 nations. The National Institute of Academic Anaesthesia has provided funding to co-ordinate UK centres.
REC name
West Midlands - Solihull Research Ethics Committee
REC reference
23/WM/0082
Date of REC Opinion
1 Jun 2023
REC opinion
Further Information Favourable Opinion