Mindfulness-Based Stress Reduction in Multiple Sclerosis
Research type
Research Study
Full title
Mindfulness-Based Stress Reduction in Multiple Sclerosis - a randomised controlled trial.
IRAS ID
146435
Contact name
Robert Simpson
Contact email
Sponsor organisation
NHS Greater Glasgow and Clyde
Research summary
This application concerns a proposed randomised controlled trial evaluating the use of Mindfulness-based stress reduction (MBSR) in people with multiple sclerosis (MS) in secondary care.
MS is an inherently stressful condition, and stress is thought to exacerbate MS. Mental health problems are common in MS, can impair quality of life, and lead to higher rates of suicide.
Prior research has shown that cognitive behavioural therapy (CBT) can help mitigate stress and diminish disease activity in MS, but effects are short lived and there is thus a need to explore whether other psychological approaches might be more beneficial in this regard.
MBSR is another psychological stress reduction technique that is thought to operate differently to CBT, via cultivating a state of 'meta-cognitive awareness' (‘intentionally attending, moment by moment, with openness and non-judgementalness’) and has been shown to be helpful when used in other long term conditions, such as chronic pain and anxiety, whilst Mindfulness-based cognitive therapy (MBCT - a derivative of MBSR) is effective in treating recurrent depression. All of these conditions are common in MS. However, mindfulness based interventions have not been well studied in MS.
We propose to carry out a feasibility study to assess how acceptable and accessible MBSR is as a stress reduction technique in people with MS. We would seek up to 50 participants who would then be randomly assigned to receive either MBSR or their usual care. We would seek measurements of health and wellbeing before, immediately following, and 3 months following the MBSR intervention. This will include basic demographic information (age, gender, ethnicity), measures of mental health, and physical health, as well as qualitative semi-structured interviews with selected participants. After this we would offer the MBSR to the control group.REC name
South East Scotland REC 01
REC reference
14/SS/0091
Date of REC Opinion
27 May 2014
REC opinion
Further Information Favourable Opinion