Mid­term outcomes of highly cross­linked polyethylene hip replacements

• Research type

  Research Study

• Full title

  Mid­-term outcomes of highly cross­-linked polyethylene hip replacements

• IRAS ID

  119827

• Contact name

  Robert Middleton

• Contact email

  robert.middleton@rbch.nhs.uk

• Sponsor organisation

  The Royal Bournemouth Hospital

• Research summary

  At least seven years prior to participation in the current study, patients underwent a total hip replacement (THR) as part of a multi­centre randomised controlled trial (RCT) on “The effect of prosthetic head size on hip dislocation and wear following total hip replacement (CPT/DHOH­11/00)” (South West MREC Ref: 01/6/10). The type of replacement they received contained a relatively new type of plastic liner. Patients will now be asked to return for review again 7 to 10 years following THR, enabling us to gain a better understanding of how these types of prostheses are now functioning.

  All patients will be asked to have x­rays which are routinely done as part of follow­up of THR, to determine:
  1. to what extent there has been any wearing away of the plastic liner of the prosthesis (polyethylene wear), and 2. whether the hip prosthesis has moved within the bone since it was implanted.

  All patients will also be asked to complete a questionnaire about whether their hip has dislocated or ever feels unstable, and another questionnaire about hospital attendances. Information on any operations they may have had will also be obtained.
  In addition, patients who underwent primary THR will be asked to have one CT scan of the hip, to determine bone loss around the prosthesis (periprosthetic osteolysis.

  This study will provide surgeons with a better understanding of whether the short­term benefit of using a larger ball and socket joint, namely a lower risk of hip dislocation, is still evident seven years after THR. Importantly, we will also determine whether there are any new side effects, such as increased loss of bone or increased wearing away of the plastic liner. This will help surgeons choose the most appropriate type of prosthesis for THR.

• REC name

  South Central - Oxford B Research Ethics Committee

• REC reference

  13/SC/0275

• Date of REC Opinion

  6 Aug 2013

• REC opinion

  Further Information Favourable Opinion