Mechanical testing of a patella tendon graft for ACL reconstruction

• Research type

  Research Study

• Full title

  The stratification, implementation, and functional assessment of a decellularised human bone-patella tendon-bone allograft for use in anterior cruciate ligament reconstruction.

• IRAS ID

  275493

• Contact name

  Anthony Herbert

• Contact email

  a.herbert@leeds.ac.uk

• Sponsor organisation

  University of Leeds

• Duration of Study in the UK

  1 years, 11 months, 30 days

• Research summary

  This study will investigate the mechanical properties of bone-patella tendon-bone grafts harvested from human cadavers. This tissue is used to reconstruct the anterior cruciate ligament (ACL) following injury. By comparing the graft mechanical properties to those of the anterior cruciate ligament from cadavers with different physical characteristics, the most appropriate grafts can be selected for a particular cohort of patients. This will enable NHS Blood & Transplant Tissue & Eye Services (NHSBT:TES) to provide a stratified product with Good Manufacturing Process (GMP) for clinical transplantation.

• REC name

  Yorkshire & The Humber - Leeds East Research Ethics Committee

• REC reference

  20/YH/0197

• Date of REC Opinion

  29 Jun 2020

• REC opinion

  Favourable Opinion