Measurement of metabolic activities in human tissue and cells
Research type
Research Study
Full title
Measurement of metabolic activities in human tissue and tissue cells to assess new drugs for drug development in the Pharmaceutical and Biotech Industries.
IRAS ID
134158
Contact name
Stuart Wood
Contact email
Research summary
The aim of this application is the collection of fresh human normal tissues from the University Hospitals of Leicester by Quotient Bioresearch (Rushden) Ltd for use for research purposes. Fresh human tissues are very important for research and especially for in vitro and preclinical study evaluation of new medical treatment. Quotient Bioresearch (Rushden) Ltd use human tissue and cells isolated from human tissues to assess new drugs for drug development in the Pharmaceutical and Biotech Industries. The objective of the research studies is to test the effectiveness and safety of potential new medicines in humans.
Regulatory authorities such as the U.S. Food and Drug Admistration (FDA) in U.S.A. and the European Medicines Agency (EMA) in Europe which are responsible for the regulation of medicines in the Western World both recommend the use of in vitro techniques using human tissues and cells in drug development.
Quotient Bioresearch (Rushden) is a Contract Research Organization (CRO) founded more than 10 years ago which is experienced in various types of in vitro drug metabolism services and assay development which are used to study the metabolism, transport and safety (toxicity) of potential new drugs.Quotient Bioresearch offers modern in vitro techniques within a multi-accredited (GLP, GCP &GMP) (Good Laboratory Practice, Good Clinical Practice & Good Manufacturing Practice) Facility for providing custom-made R&D solutions to the pharmaceutical, animal health and agrochemical industries. The in vitro techniques employed includes pre-clinical studies and numerous In Vitro services.
REC name
East Midlands - Leicester South Research Ethics Committee
REC reference
14/EM/0019
Date of REC Opinion
22 Jan 2014
REC opinion
Favourable Opinion