MDR

  • Research type

    Research Study

  • Full title

    Risk factors for the development of bilateral Meniere's disease and the establishment of a national Meniere's disease registry.

  • IRAS ID

    275749

  • Contact name

    John Phillips

  • Contact email

    john.phillips@nnuh.nhs.uk

  • Sponsor organisation

    Norfolk & Norwich University Hospitals NHS Foundation Trust

  • Duration of Study in the UK

    1 years, 1 months, 1 days

  • Research summary

    Recent research has suggested that Ménière’s disease may be a consequence of a number of individual conditions rather than developing from a single cause. This means that determining the different conditions that cause Ménière’s disease will help us to provide effective treatments. Experience from other similar medical conditions has taught us that the best method to identify different causes of a condition is via a process called ‘clinical subtyping’. We intend to set up a large Ménière’s disease database in order to allow us to subtype Ménière’s disease. More specifically, our proposed project aspires to achieve two aims. We intend to investigate a sub-type of Ménière’s disease, bilateral disease, i.e. both ears affected. We hope to identify what features predict an individual developing bilateral Ménière’s disease. Secondly, we hope to test the feasibility of expanding the database across the whole of the UK to involve all Ménière’s disease patients. This will allow many other features of Ménière’s disease to be used to establish sub-types and help predict the best treatment for individual patients.

  • REC name

    North West - Liverpool Central Research Ethics Committee

  • REC reference

    19/NW/0752

  • Date of REC Opinion

    20 Jan 2020

  • REC opinion

    Further Information Favourable Opinion