Maternal Serum PAPP-A levels and pregnancy outcomes

• Research type

  Research Study

• Full title

  Association of serum PAPP A levels in first trimester with small for gestational age and other adverse Pregnancy outcomes: systematic review and retrospective cohort study.

• IRAS ID

  164304

• Contact name

  Ashwini Bilagi

• Contact email

  abilagi@yahoo.com

• Sponsor organisation

  Birmingham Women's Hospital

• Duration of Study in the UK

  0 years, 9 months, 31 days

• Research summary

  This project will aim:
  1. To perform a systematic review to assess the predictive accuracy of first trimester serum PAPP-A (alone or in combination with other markers e.g. first trimester uterine artery Doppler) for adverse pregnancy outcomes measured in terms of pregnancy loss, perinatal mortality, preterm birth, intra-uterine death (IUD) and small for gestational age (SGA) .
  2. To assess the predictive accuracy of first trimester serum PAPP-A alone or in combination with other biometric indicators for adverse pregnancy outcome in the population at BWNFT.

• REC name

  North West - Preston Research Ethics Committee

• REC reference

  14/NW/1394

• Date of REC Opinion

  12 Nov 2014

• REC opinion

  Further Information Favourable Opinion