Management of patients’ reported histories of adverse drug reactions
Research type
Research Study
Full title
The perceptions of hospital inpatients, carers, and healthcare staff, surrounding management of patients’ reported histories of adverse drug reactions: an exploratory qualitative study
IRAS ID
321750
Contact name
Bryony Dean Franklin
Contact email
Sponsor organisation
Imperial College London, Research and Governance Integrity Team
Duration of Study in the UK
1 years, 0 months, 24 days
Research summary
An adverse drug reaction is a response to a medication that is not intended. There are some adverse drug reactions that are a risk to patient safety. An example of this then would be where a patient who experienced a serious or very unpleasant reaction from a medication previously, receives another dose of the same medication. There are two contrasting problems that can happen when healthcare professionals care for patients with a reported history of adverse drug reactions:
1. Patients can receive a medication to which they have a past history of experiencing serious or unpleasant reactions.
2. Healthcare professionals might not prescribe or administer a medication to a patient, which might the best treatment option for them. This happens because the healthcare professionals wrongly believe that the patient previously experienced a serious or unpleasant reaction from this medication, even when this is not the case.
These two patient safety problems still happen even when healthcare settings use computer systems, called clinical decision support systems, which are put in place to help minimise such risks from happening. There are a number of things that healthcare professionals do ('practices') that can affect how patients with reported histories of adverse drug reactions are cared for. These include how healthcare professionals ask patients about their histories of adverse drug reactions, how they document this information in the patient health records, and how they use the clinical decision support systems.We aim to improve the safety of medication use in hospital inpatients with a reported history of adverse drug reactions, by understanding current practices that are used by healthcare professionals when they are caring for such patients. We also want to understand the expectations and experiences that patients, carers, and healthcare staff have of these practices.
REC name
Yorkshire & The Humber - Bradford Leeds Research Ethics Committee
REC reference
23/YH/0167
Date of REC Opinion
29 Aug 2023
REC opinion
Further Information Favourable Opinion