Magnetic Seed localisation of breast cancers Version 1

  • Research type

    Research Study

  • Full title

    Safety and feasibility study of the use of Magnetic Seeds for the localisation of breast cancers for surgical excision

  • IRAS ID

    185589

  • Contact name

    James Harvey

  • Contact email

    james.harvey@uhsm.nhs.uk

  • Sponsor organisation

    University Hospital of South Manchester

  • Clinicaltrials.gov Identifier

    NCT02635737

  • Duration of Study in the UK

    0 years, 10 months, 24 days

  • Research summary

    Many breast cancers are not able to be felt by patients or by breast surgeons because either they do not form a lump that we can feel, or mainly because they are picked up at an early stage before they become large enough to be felt. For surgeons to remove these cancers, the site of the cancer is marked for surgery, this usually involves having a metal wire inserted into the breast and the cancer, which the surgeon can follow during surgery to find the cancer. This study aims to assess the ability of a magnetic seed placed before surgery to direct a surgeon accurately to the cancer. The surgeon will use a small probe that can detect magnetism to help to find the marker. The method has the potential to direct surgeons more accurately to the cancer site than following a wire, particularly in a large breast, which can be difficult and involve removing unecessary tissue. Placement of a seed in advance logistically makes it easier for staff and patients as the seed can be placed many days in advance of surgery, unlike a wire which requires placement on the morning of surgery. This means a patient can come in on the day of surgery ready to have their operation straight away. There is the potential for the magnetic seed to more accurately show surgeons the site of the cancer and to reduce the amount of unnecessary tissue removed from the breast.

  • REC name

    North West - Haydock Research Ethics Committee

  • REC reference

    16/NW/0092

  • Date of REC Opinion

    22 Feb 2016

  • REC opinion

    Favourable Opinion