MACCE after endoscopic vein harvest for CABG
Research type
Research Study
Full title
Major adverse cardiac and cerebrovascular event (MACCE) & patients’ Quality of life (QOL) after Endoscopic Vein Harvesting as compared to open vein harvest for coronary artery bypass grafting. (MAQEH Study)
IRAS ID
172866
Contact name
Heyman Luckraz
Contact email
Sponsor organisation
The Royal Wolverhampton NHS Trust
Duration of Study in the UK
0 years, 3 months, 0 days
Research summary
Most patients undergoing coronary artery bypass grafting (CABG) will require long saphenous vein (LSV) harvesting from the leg. This has been reported to be associated with a significant morbidity (leg swelling, pain, infection, bruising, wound discharge) in up to 50% of patients.
Endoscopic vein harvesting (EVH) which has been reported to be associated with a reduction in these complications was implemented within our service in 2012. Although some initial reports of concerns regarding graft patency when the LSV is harvested by EVH, NICE and European Cardiology Society (ESC/EACTS) guidelines 2014 supported the use of the EVH technology.
Last year a service evaluation in our department showed significant cost benefit of EVH as compared to open vein harvest (OVH) in a matched group (50 EVH and 50 OVH patients). The purpose of this study is to evaluate this group further to assess the incidence of MACCE (Major adverse cardiac and cerebrovascular event) and patient's quality of life (QOL) at least 1 year after their surgery.
MACCE will be assessed by contacting the patient’s GP and/or Cardiologist and QOL questionnaire (SF12v2) will be sent to patients along with a patient information sheet. It is estimated that data collection would be completed within 3 months of start.REC name
South Central - Oxford A Research Ethics Committee
REC reference
15/SC/0178
Date of REC Opinion
15 Apr 2015
REC opinion
Further Information Favourable Opinion