Lymphoma CAR T registry

  • Research type

    Research Database

  • IRAS ID

    331212

  • Contact name

    Andrea Kuhnl

  • Contact email

    andrea.kuhnl@nhs.net

  • Research summary

    CAR T registry

  • REC name

    London - South East Research Ethics Committee

  • REC reference

    24/LO/0527

  • Date of REC Opinion

    12 Jul 2024

  • REC opinion

    Favourable Opinion

  • Data collection arrangements

    The Registry will collect and store routine clinical data on adult lymphoma patients treated with CAR T at participating UK centres. Data will be retrospective, i.e. already obtained and recorded as per standard practice at the treating centre. Data will be sent and stored on secure NHS server, on password protected files. Data sent to the Registry will not contain any personal patient data, but pseudonymised NHSE IDs generated through the UK CAR T submission process. Data will be managed and sustained by investigators from the KCH Haematology Unit as part of the CAR T clinical programme.

  • Research programme

    The NHS National CAR T Clinical panel (NCCP) comprising CAR T clinicians, patient representatives and independent experts, have initiated the idea of setting up a UK-wide registry at KCH and will oversee the research programme of the Registry. The NCCP will periodically review clinical analyses conducted using the Registry data, to ensure that data are used to produce knowledge valuable to the treatment of lymphoma patients and that data are disseminated as appropriate.

  • Research database title

    CAR T registry

  • Establishment organisation

    King's College Hospital NHS FT

  • Establishment organisation address

    Haematology Research Unit

    Ground floor, Hambleden Wing,Denmark Hill

    London

    SE5 9RS