LVT Registry
Research type
Research Study
Full title
Observational registry to determine the predictors and outcomes of patients at risk of and diagnosed with Left Ventricular Thrombus
IRAS ID
336025
Contact name
Dan Jones
Contact email
Sponsor organisation
Queen Mary University of London
Duration of Study in the UK
3 years, 0 months, 30 days
Research summary
Left Ventricular Thrombus (LVT) is a blood clot that can develop in a poorly functioning heart. In around 1 in 6 patients who have had a heart attack or diagnosed with heart failure tend to develop blood clots in their main heart chamber. Having a blot clot in the main heart chamber can lead to serious complications such as stroke. Treatment for blood clots is blood thinning medications, which if taken for a prolonged period of time can result in bleeding which further complicates treatment.
We hope to gather information to better understand the factors associated with blood clot formation and management in the lower left chamber of the heart. This understanding will hopefully enable us and others to improve management of this condition in the future and therefore help the wider population.
As part of this study, bloods and scan results will be recorded and we will complete a short quality of life questionnaire.
When participants come in for routine MRI scan, we may capture additional images for further research analysis.
A sample of blood no more than one tablespoon will be collected for research analysis at the same time as routine blood test. This will occur at baseline and at around 6 months. At 12 months we will repeat the quality of life questionnaire and collect final data.REC name
London - Westminster Research Ethics Committee
REC reference
24/LO/0091
Date of REC Opinion
18 Mar 2024
REC opinion
Further Information Favourable Opinion