Longitudinal Web-based Profiling of Students with Rare Diseases

  • Research type

    Research Study

  • Full title

    Longitudinal Web-based Profiling of Students with Rare Diseases in Schools in England - Supporting Teachers and Improving Care

  • IRAS ID

    316909

  • Contact name

    Paramala Santosh

  • Contact email

    paramala.1.santosh@kcl.ac.uk

  • Sponsor organisation

    King's College London

  • Clinicaltrials.gov Identifier

    n/a, n/a

  • Duration of Study in the UK

    2 years, 0 months, 1 days

  • Research summary

    Mental health difficulties in children are significantly prevalent across schools in England. Rare and severe psychiatric disorders of low prevalence in children are often neglected. Approximately 6000 children are born in the United Kingdom every year with an undiagnosed genetic condition, otherwise known as a syndrome without a name (SWAN). Some of these individuals may have a rare disease (RD) but without the correct diagnosis, they face multiple barriers to receiving treatment and support, causing psychological distress. School teachers care for children and young people (CYPs) with RDs daily but receive little to no training or support. Supporting school teachers to identify and teach children with undiagnosed conditions and RDs may reduce delays in diagnosis and improve the wellbeing of patients, parents and teachers.

    This is an exploratory 2-year study assessing the rare disease profiles and neuropsychiatric symptoms of CYPs at special and mainstream schools in England. Alongside, this study will assess the wellbeing of parents and teachers caring for CYPs. This will be done in five stages. First, (1) a questionnaire assessing teacher wellbeing in the context of RD management will be created using focus groups. Next, this study will (2) recruit CYPs, teachers and parents from both special and mainstream schools and (3) obtain their informed consent. Following, (4) RD profiles and parent and teacher wellbeing will be assessed using the web-based HealthTrackerTM platform. Psychoeducational support packages will be (5) developed based on the assessment results and (6) participants will complete follow-up assessments at 6 monthly intervals to understand RD symptom progression. The psychoeducational packages will be developed according to symptom clusters, rather than specific RD diagnoses, to ensure that CYPs with SWAN are included.

  • REC name

    South Central - Oxford C Research Ethics Committee

  • REC reference

    24/SC/0168

  • Date of REC Opinion

    12 Jun 2024

  • REC opinion

    Unfavourable Opinion