Longitudinal Cardiovascular Health
Research type
Research Study
Full title
A longitudinal monitoring study of cardiovascular health in the Essex region
IRAS ID
133142
Contact name
Leon Webster
Contact email
Sponsor organisation
Basildon and Thurrock University Hospital NHS Foundation Trust
Research summary
This research project is a longitudinal study of cardiovascular health and disease within the Essex region. The study involves analysing data for patients who have visited the Essex Cardiothoracic Centre (ECTC) in Basildon, Essex for at least one type of coronary surgery procedure. The study will last for two years and therefore in addition to using pre-existing data since the ECTC opened in July 2007, future treatments over this period will also be factored into the statistical analysis.
The primary objective is to identify trends which exist, identification of such trends may allow for more efficient resource allocation and treatment planning for patients.
Statistical analysis for both in-hospital and long-term adverse events (mortality, heart attacks, stroke, emergency coronary artery bypass grafts) will identify the types of surgery and also the patient characteristics/risk factors which are associated with the high risk, those which have been used by existing risk prediction models are: age; gender; priority of surgery etc.
By analysing risk factors, a prediction model can be constructed. This model uses the presence of certain risks as weighted coefficients to produce a score value which can be used to categorise patients into various risk groups (very low, low, moderate, high and very high). This assigned risk group will represent the estimated likelihood of a new patient experiencing an adverse event.
The long-term analysis will include several time intervals following a given treatment date. These will be 1, 2, and 6 months; and 1, 3, and 5 years (if such data is available). Patient readmission for subsequent surgery will also be factored into the study; this will identify which types of surgery favour high readmission rates.
Following analysis of the ECTC data, a comparison against national health databases (BCIS, MINAP) can then be performed allowing performance levels to be assessed.
REC name
West Midlands - Solihull Research Ethics Committee
REC reference
13/WM/0289
Date of REC Opinion
15 Jul 2013
REC opinion
Favourable Opinion