Living Lab Radiogenomics v1.0, 24 Jan 2024

  • Research type

    Research Database

  • IRAS ID

    339548

  • Contact name

    Kevin Blyth

  • Contact email

    Kevin.Blyth@glasgow.ac.uk

  • Research summary

    Living Lab Radiogenomics Research Database

  • REC name

    West of Scotland REC 4

  • REC reference

    24/WS/0024

  • Date of REC Opinion

    12 Apr 2024

  • REC opinion

    Further Information Favourable Opinion

  • Data collection arrangements

    The data stored in this project comes from 1,400 patients with lung cancer diagnosed between 2015-2020. The types of data stored will include clinical information (e.g. age, sex, smoking status, date of diagnosis, outcome of treatment), copies of scans used to detect the lung cancer and track response to treatments (e.g. CT scans) and results of various laboratory tests done on samples of the tumour (e.g. DNA sequencing). We have not been able to seek consent from the patients involved as most will unfortunately have died, reflecting the poor survival from this disease. Creating this database will allow researchers to use advanced computing to find patterns in the data that could lead to better prediction of response and survival and faster development of new treatments.

    The data is currently being collected by NHS partners who can securely access routine NHS records. These staff will remove identifiable information before the data is transferred to the database, making it impossible to identify any individual. Since the database will have all the advanced computing analysis tools inside it, we will never share data with researchers who apply to use the database. Researchers will simply run their tests inside the database and export results.

  • Research programme

    This project is part of the University of Glasgow’s Living Laboratory programme. Funded by a £38M grant from the government, the Living Lab aims to deliver improved healthcare outcomes, economic development and scientific progress in Glasgow and beyond. In addition to creating new knowledge that will help cancer patients everywhere, the programme will stimulate job creation and economic development in the local Govan community and the wider Glasgow area. This database will help deliver these community impacts. Bringing the various data types together in one location will let research teams from all over the world run experiments while preserving patient privacy at a scale not possible before. This will not only accelerate progress in cancer care it will also make Glasgow an attractive place for health science companies to invest, bringing the jobs and wider society benefits promised by the Living Lab programme. The database will also support the lung cancer patient community. Lung cancer remains the commonest cause of cancer-related death in Scotland and this project will accelerate research into new diagnostic tests, better ways of predicting response to treatment and development of new drugs.

  • Research database title

    Living Lab Radiogenomics Research Database

  • Establishment organisation

    University of Glasgow

  • Establishment organisation address

    University Avenue

    Glasgow

    G12 8QQ