lIfestyle iNterventionS for PaIn ReliEf (INSPIRE) in TKR patients

• Research type

  Research Study

• Full title

  Molecular signatures of endocannabinoid induced pain relief in humans: lifestyle interventions, systemic and localised changes.

• IRAS ID

  323225

• Contact name

  Thomas Kurien

• Contact email

  thomas.kurien@nottingham.ac.uk

• Sponsor organisation

  University of Nottingham

• Duration of Study in the UK

  1 years, 9 months, 3 days

• Research summary

  This study is a 2x2 diet and exercise intervention study to explore their effects on relieving knee pain. Both the diet and exercise interventions will be carried out for a total period of 6 weeks and will include 60 participants with a diagnosis of Knee Osteoarthritis in each arm. The diet arm will use inulin fibre ( a common food supplement) and the exercise arm will involve mild-moderate exercise routines which can be performed without support/ supervision.

• REC name

  South Central - Berkshire B Research Ethics Committee

• REC reference

  23/SC/0056

• Date of REC Opinion

  16 Mar 2023

• REC opinion

  Further Information Favourable Opinion