LACUNAR-CA
Research type
Research Study
Full title
Understanding the relationship between controlling risk factors and cerebral haemodynamic changes in lacunar stroke, and its interaction with ageing.
IRAS ID
335809
Contact name
Jatinder Minhas
Contact email
Sponsor organisation
University of Leicester
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
Lacunar stroke is a common cause of stroke across all ages and is caused by damage to deep tissues within the brain that do not manage high blood pressure or blood sugar very well. The damage caused often takes time to settle and can lead to a higher risk of further stroke episodes. There is little known about the brain blood flow changes in this condition and it is less researched as the symptoms can sometimes be milder and in younger (<50 years) or very old people (>85 years). This PhD studentship will look at “furring” of the brain blood vessels in ageing and in lacunar stroke, look at differences and try to also compare to healthy ageing in those without lots of vascular problems like high blood pressure. The techniques used are cutting edge and patient groups tell us that the risk of having another stroke after these events is a real concern and so trying to stop this through having a greater understanding of the disease is important. We will use cutting edge ultrasound techniques to do this, we have lots of experience of using these in acute stroke though few studies exist to date in lacunar stroke.
REC name
North East - Newcastle & North Tyneside 2 Research Ethics Committee
REC reference
24/NE/0032
Date of REC Opinion
18 Mar 2024
REC opinion
Further Information Favourable Opinion