Kidney Donor GFR study-comparison of eGFR and mGFR

• Research type

  Research Study

• Full title

  A study to assess accuracy, precision and bias of creatinine based eGFR equations (MDRD and CKD EPI), Cystatin C based eGFR equation compared to measured (Iohexol) GFR in kidney donors

• IRAS ID

  261221

• Contact name

  Mysore Phanish

• Contact email

  m.phanish@nhs.net

• Sponsor organisation

  Epsom and St helier University Hospitals NHS trust

• Duration of Study in the UK

  0 years, 3 months, 9 days

• Research summary

  Assessment of kidney donors includes measurement of GFR using plasma clearance of Iohexol. In addition, kidney function is routinely assessed at St Helier hospital using eGFR derived from serum creatinine and Cystatin C. This gives us unique opportunity to use existing data to compare 2 eGFR values (CKD EPI and Cystatin C) to mGFR (Iohexol GFR). The study uses data already obtained as part of routine clinical care and does not involve any extra tests.

• REC name

  Yorkshire & The Humber - South Yorkshire Research Ethics Committee

• REC reference

  19/YH/0195

• Date of REC Opinion

  18 Jun 2019

• REC opinion

  Favourable Opinion