iST-AN: Individual Schema-mode Therapy for Anorexia Nervosa
Research type
Research Study
Full title
Individual Schema-mode Therapy for Anorexia Nervosa: a pilot case series
IRAS ID
151045
Contact name
Calum G Munro
Contact email
Sponsor organisation
NHS Lothian
Duration of Study in the UK
3 years, 1 months, 30 days
Research summary
A reliably effective treatment model for anorexia nervosa is yet to emerge. Recent clinical trials of psychological therapies over 20-30 sessions, have shown modest benefits. There is therefore a need to test new treatments to find more effective treatments. Clinical trials of Schema Therapy have shown low rates of drop-out, which is often a problem in treatment of anorexia nervosa. Treatment with Schema Therapy, for signifiacntly longer than 20-30 sessions, has been shown to be effective for other complex mental health problems.This pilot study is therefore designed to pilot the use of individual Schema Therapy for people with Anorexia Nervosa (iST-AN).
This study is a case-series pilot study. The study will answer the principal research question: Does individual Schema-mode Therapy, adapted for eating disorders, have the potential to improve symptoms, quality of life and weight in people with moderate-severe anorexia nervosa? It will also address secondary research questions: Can people with moderate-severe anorexia nervosa be recruited to, and kept engaged in, a study of iST-AN treatment? What is the ideal length of iST-AN treatment? What is the relationship between self-criticism, body shame, or unhelpful psychological 'modes' and clinical outcome?
Fifteen people with moderate-severe Anorexia Nervosa will be recruited from referrals to a specialist eating disorders outpatient service. The study will deliver 65 sessions of Schema Therapy for anorexia nervosa (iST-AN), over a 24 month period, alongside any additional medical or dietetic management required. Standard outcome measures will be collected at 6 month intervals. The research team have expertise in eating disorders research, schema therapy for severe anorexia nervosa and are all members of the local clinical service. The study will take place over a 3 year period.REC name
South East Scotland REC 02
REC reference
15/SS/0066
Date of REC Opinion
4 May 2015
REC opinion
Favourable Opinion