ISpy COVID - seroprevalence in paediatric dialysis and transplant [COVID-19]
Research type
Research Study
Full title
ISpy COVID: CoronavIrus antibodieS in vulnerable Paediatric patients with kidneY disorders
IRAS ID
287488
Contact name
Jon Jin Kim
Contact email
Sponsor organisation
Nottingham University Hospital
Duration of Study in the UK
1 years, 3 months, 22 days
Research summary
As at 18 May, there were 144,127 confirmed Covid-19 cases in England, of which 2,330 (1.6%) were children and young persons (CYP) under 20 years old. For CYP on dialysis or with a renal transplant, only five confirmed cases have been reported to the UK Renal Registry (UKRR), all with mild disease. Whether this small case number is due to effective shielding measures by the families, or undetected mild to asymptomatic cases is not known. Knowing the true prevalence of Covid-19 in this ‘extremely vulnerable’ group is important for consideration of safe return to school and work.
To this end, we will analyse surplus samples stored in the laboratory for SARS-Cov2 antibodies. Excess sera will be pseudo-anonymised by the direct care medical team before testing by the laboratory team. We will also collect basic clinical information to identify risk factors for contracting the virus and susceptibility to COVID-19. This study will provide useful information regarding the number of affected patients, how long antibodies last and whether they protect against re-infection.
REC name
N/A
REC reference
N/A