ISAIAH- InveStigation of AnaemIA in Hospital
Research type
Research Study
Full title
PREVALENCE AND INVESTIGATION OF LABORATORY DIAGNOSED ANAEMIA IN SECONDARY CARE
IRAS ID
233509
Contact name
James Plumb
Contact email
Sponsor organisation
University Hospital Southampton NHS Foundation Trust
Duration of Study in the UK
0 years, 9 months, 29 days
Research summary
Anaemia, defined as a reduction in circulating haemoglobin (Hb) concentration ([Hb]) of < 120 g l-1 in non-pregnant females and < 130 g l-1 in males is a common haematological disorder encountered in diseases such as cancer, inflammatory bowel disease (IBD), chronic heart failure (CHF), chronic kidney disease (CKD), chronic liver disease (LD) and in patients preoperatively. Anaemia, regardless of underlying cuase is associated with reduced quality of life, chronic fatigue and poor prognosis in CHF and malignancy, as well as poor postoperative outcomes in both cardiac and non-cardiac surgery. Population studies in the UK have found anaemia to be more prevalent than diabetes, with a similar incidence to cardiovascular disease.
The purpose of this study is to evaluate current routine practice in the diagnosis and investigation of anaemia in secondary care. Using data from a large teaching hospital we will develop an understanding of how a laboratory diagnosis of anaemia, i.e. a haemoglobin concentration below the normal reference range set by the world health organisation (WHO), is investigated and the economic impact of these investigations.
REC name
South Central - Hampshire A Research Ethics Committee
REC reference
17/SC/0524
Date of REC Opinion
20 Oct 2017
REC opinion
Favourable Opinion