Iron homeostasis in pregnant women with overweight/obesity V1

  • Research type

    Research Study

  • Full title

    Inflammatory and genetic factors involved in iron homeostasis in pregnant women with overweight and obesity.

  • IRAS ID

    321833

  • Contact name

    Mary McCann

  • Contact email

    mt.mccann@ulster.ac.uk

  • Sponsor organisation

    Ulster University

  • Clinicaltrials.gov Identifier

    15/NI/0068, Office for Research Ethics Committees Northern Ireland; WT 14/49, WHSCT ; NCT02713009, ClinicalTrials.gov

  • Duration of Study in the UK

    2 years, 2 months, 6 days

  • Research summary

    Obesity is the most prevalent health condition in women of reproductive age with an increasing global trend, and is associated with increased severe obstetric complications, including increased maternal and perinatal mortality. Furthermore, iron deficiency is the most common micronutrient deficiency in women of reproductive age and is associated with serious perinatal complications, increased risk of neonatal anemia, and neurodevelopmental impairment in infants. We hypothesize that women with overweight and obesity are at increased risk of iron deficiency, not only due to poorer diet quality, but also to potential metabolic factors that are exacerbated by obesity. Findings from this research will be used to inform nutrition policy on appropriate iron deficiency screening in pregnancy which may be dependent upon pre pregnancy body mass index.

  • REC name

    HSC REC B

  • REC reference

    23/NI/0087

  • Date of REC Opinion

    21 Jul 2023

  • REC opinion

    Further Information Favourable Opinion