Investigating the relationship between hypoxia and metabolism

• Research type

  Research Study

• Full title

  Investigating the relationship between hypoxia and metabolism.

• IRAS ID

  127265

• Contact name

  Christopher Imray

• Contact email

  christopher.imray@uhcw.nhs.uk

• Sponsor organisation

  UHCW NHS Trust

• Research summary

  The purpose of this study is to investigate how exposure to hypoxia over extended periods can impact metabolic function, at both physiological and biochemical levels.
  Hypoxia occurs in a variety of medical conditions: chronic obstructive pulmonary disorders (COPD), asthma, pulmonary fibrosis, apnoea or congestive cardiac failure, to name a few. The relationship between these disease and metabolic syndrome and inflammatory response has recently become evident. This study will enable key relationships to be identify, and accurately quantify, the biochemical and physiological variables affected by hypoxic exposure; creating new hypotheses, with supporting evidence and pilot data, to assist in explaining the affects of hypoxia on metabolism, potentially leading to the diagnosis and treatment.

• REC name

  West Midlands - Coventry & Warwickshire Research Ethics Committee

• REC reference

  13/WM/0327

• Date of REC Opinion

  4 Sep 2013

• REC opinion

  Favourable Opinion