Investigating link between GAD, Stiff person syndrome and Type 1 DM

• Research type

  Research Study

• Full title

  Immune responses to Glutamic Acid Decarboxylase (GAD) peptides in a patient with type I diabetes and stiff person syndrome

• IRAS ID

  192428

• Contact name

  david Bowen-Jones

• Sponsor organisation

  Wirral University teaching hospital

• Duration of Study in the UK

  0 years, 2 months, 1 days

• Research summary

  This single person study will aim to examine the link between Type 1 diabetes and the neurological condition stiff person syndrome.

  Both conditions are known to be auto-immune in nature. By testing one patients blood for immunological factors we hope to establish exactly which autoimmune components are common to both diseases.

  In order to do this, 4 blood samples will be taken from one patient (separated by 1 month) who has both conditions. The patient has agreed to this verbally and formal, written consent will be sought.

  The responses will then be compared to 12 control samples. Blood samples will be taken from 12 control individuals (6 with type 1 and diabetes and 6 without).

• REC name

  East of England - Cambridge Central Research Ethics Committee

• REC reference

  17/EE/0039

• Date of REC Opinion

  7 Mar 2017

• REC opinion

  Further Information Favourable Opinion