Interaction of Immune Cells and Renal Cancer in a Microfluidic Device
Research type
Research Study
Full title
Investigating the Effects of Immune Cells on Renal Cancer Biopsies Maintained in Bespoke Microfluidic Devices
IRAS ID
329289
Contact name
John Greenman
Contact email
Sponsor organisation
University of Hull
Duration of Study in the UK
2 years, 5 months, 30 days
Research summary
This study seeks to create microfluidic devices that can imitate how the immune cells of a patient interact with cancer biopsies taken from the same patient. The microfluidic devices allow human tissue to be studied in an environment more representative of the human body than animal models or tumour cell lines.
This device could better show how certain anti-cancer drugs, both traditional and novel, change how the immune cells interact with the cancer cells. This could be used to predict which treatments may work best on a patient before they undergo therapy. It could also be used in research settings to better predict the effectiveness of novel anti-cancer drugs under development.REC name
Yorkshire & The Humber - South Yorkshire Research Ethics Committee
REC reference
23/YH/0236
Date of REC Opinion
9 Nov 2023
REC opinion
Favourable Opinion