Inflame COVID19 study [COVID-19]
Research type
Research Study
Full title
Identification of Novel Factors Leading to Activated Macrophage Expansion in COVID19 and related conditions to guide targeted intervention. Inflame COVID19 study.
IRAS ID
286016
Contact name
Michael R Ardern-Jones
Contact email
Sponsor organisation
University Hospital Southampton NHS Trust
Duration of Study in the UK
4 years, 0 months, 0 days
Research summary
This project aims to undertake a high-resolution analysis of previous cases of COVID19 infection to determine from all available clinical data recorded over the timeline of admission, who might benefit best from specific interventions designed to target a hyper inflammatory response in this condition. This approach offers a timely contribution to the field where the first phase of unselected clinical trials is already underway, and the second phase will require a more targeted approach. Southampton offers a unique opportunity to undertake this work, as it is widely accepted that we lead the UK in clinical data informatics. This project links our research efforts at the clinical level to current understanding of disease pathways, for which we have effective interventions and the problem we aim to solve is, who will benefit from the available novel anti-inflammatory approaches and when should this treatment be given?
REC name
N/A
REC reference
N/A