Infant feeding and the body burden of aluminium
Research type
Research Study
Full title
The contribution of breast and formula feeding to the body burden of aluminium in infants (0-12 months)
IRAS ID
148651
Contact name
Christopher Exley
Contact email
Sponsor organisation
THE DUDLEY GROUP NHS FOUNDATION TRUST
Duration of Study in the UK
2 years, 0 months, 1 days
Research summary
The hypothesis being tested in the study is that infant feeding, specifically combinations of breast and formula feeds, will have no influence upon the amount of aluminium retained in infants at 0 1.5, 3, 6 and 12 months of age.
The aim of the research is to study the amount of aluminium retained in infants, with particular regards to infant feeding, specifically the roles of breast milk and formula feeding as sources of dietary aluminium. There are currently no data for the amount of aluminium retained in infants in this (or any) age group.
The primary objective is to monitor urine excretion of aluminium in term infants fed breast milk, infant formula and term infants fed combinations of the two over the first 12 months of their lives. Additional variables will include urine creatinine (Crt) and urine excretion of silicon (Si).
The research will additionally monitor aluminium levels through the collection of hair samples as a secondary indicator. Both methods will be used for measuring the aluminium retention in infants. The data collected will be then used to establish if there are any relationships between the amount of aluminium retained and the type of infant feeding.
REC name
West Midlands - Black Country Research Ethics Committee
REC reference
14/WM/1114
Date of REC Opinion
13 Oct 2014
REC opinion
Further Information Favourable Opinion