Incidence of peri-prosthetic fractures with the CPT stem

• Research type

  Research Study

• Full title

  A comprehensive assessment of peri-prosthetic fractures associated with the CPT® stem in a large teaching hospital over 16 years

• IRAS ID

  287117

• Sponsor organisation

  Nottingham University Hospitals NHS Trust

• Clinicaltrials.gov Identifier

  n/a, n/a

• Duration of Study in the UK

  1 years, 0 months, 1 days

• Research summary

  Peri-prosthetic fractures (PPF) are a serious complication of total hip replacement (THR). Recent publications have suggested a higher prevalence of PPF with the cemented collarless polished tapered stem (CPT®) compared to other polished taper stem designs and a higher revision rate for PPF in the UK National Joint Registry (NJR). Nottingham began using this stem design in 2009 and have not noticed a significant cohort of patients suffering PPF, but the true incidence may be unknown as some patients may undergo fixation that is not recorded in the NJR.

  This study will retrospectively review all patients who have received the CPT stem for primary THR at a single institution and record data for specifics related to the implant (stem size, offset, head size), patient (age, gender) and technical considerations of the surgery (Canal morphology, stem alignment and quality of cementation). Using HES data all hospital admissions within this cohort with femoral fracture will be identified.

  The primary aim of this research is to define the incidence of periprosthetic fracture related to this stem design in a large consecutive series of patients in an NHS teaching hospital and if any particular risk factors can be identified.

  In order to obtain hospital episode statistics from NHS Digital it has been necessary to obtain funding for the research and this has been provided by Zimmer , the implant manufacturer. Zimmer will play no part in project design, implementation or delivery and funding is limited to the costs of the data search as advised by NHS Digital.

• REC name

  Wales REC 1

• REC reference

  21/WA/0177

• Date of REC Opinion

  9 Jun 2021

• REC opinion

  Favourable Opinion