Impact of Severity of Nausea Affecting Pregnant Women (iSNAP)
Research type
Research Study
Full title
Impact of Severity of Nausea Affecting Pregnant Women (iSNAP), an observational study exploring how quality of life is affected by severity of symptoms of nausea and vomiting in pregnancy.
IRAS ID
217779
Contact name
Catherine McParlin
Contact email
Sponsor organisation
Newcastle Joint Research Office
Duration of Study in the UK
0 years, 5 months, 31 days
Research summary
AIM: This research will compare the relationship between the severity of nausea and vomiting of pregnancy (NVP) and quality of life (QoL). It will also compare 2 different QoL questionnaires to see which one is better at measuring how the change in symptoms affects women’s lives.
BACKGROUND: Around 85% of women suffer from some degree of NVP. This can cause physical and emotional distress and reduced QoL.
Care varies between hospitals; women have reported feeling unsupported, dissatisfied, anxious and depressed.
Three recent reviews of NVP research concluded that more, good quality research was needed which focused on outcomes that were important to sufferers, such as QoL.
Questionnaires designed to measure QoL in non-pregnant populations may not be very sensitive in measuring changes in the QoL in women with NVP. A NVP specific QoL questionnaire (the NVPQoL), may be more appropriate to use but it has not been tested in the UK.
DESIGN: Women attending the Royal Victoria Infirmary with any level of NVP, who are less than 11 weeks pregnant, will be asked to participate. Nursing/midwifery staff will confirm whether it is appropriate for the research team to speak to potential participants and a member of the research team will then explain the study and obtain consent from the patient.
At this point women will be asked to complete a questionnaire about personal characteristics, symptoms, and QoL. They will then be given a second questionnaire asking about symptoms and QoL, and a pre-paid envelope and asked to complete this at two time points (day 3 and 7)and post it back. Participants will be asked if they would like a text reminder to complete this questionnaire.
The study will last four months and recruit 50 women during this time.
DISSEMINATION. The results will be published in a scientific journal and a student dissertation.REC name
London - Camden & Kings Cross Research Ethics Committee
REC reference
17/LO/0320
Date of REC Opinion
22 Feb 2017
REC opinion
Favourable Opinion