Impact of daily living activities on glucose control in those with T1D
Research type
Research Study
Full title
Characterising the impact of daily living activities on glucose control in people with type 1 diabetes: An exploratory observational study
IRAS ID
327163
Contact name
Mark Hopkins
Contact email
Sponsor organisation
University of Leeds
Duration of Study in the UK
0 years, 6 months, 27 days
Research summary
Sedentary behaviour such as sitting for long periods of time is widely recognised as being bad for our health. In people with type 2 diabetes (T2D), sitting for long periods of time is associated with poorer glucose management and an increased risk of diabetes complications. Conversely, reducing prolonged periods of sitting and increasing physical activity has been shown to improve glucose control and reduce the risk of diabetes complications in people with or at risk of developing T2D. In people with T1D, the evidence is less clear-cut and although physical activity is recommended to all individuals with T1D, much of this information is focused on exercise rather than physical activity. Importantly, exercise (higher-intensity activities such as running, swimming, and team sports) and physical activity (lower intensity day-to-day activities such as housework) are not synonymous, and the glucose responses to different types of exercise and physical activities are distinct. Because activities of everyday living make up a large proportion of the day the development of appropriate self-management strategies for the incorporation of physical activity and activities of daily living into the everyday lives of people with T1D is a priority. The first logical step here is to characterise glucose responses to different types of everyday activity, which to date, has never been undertaken.
Therefore this study will characterise the glucose responses to activities of daily living in 40 people with T1D in their own free-living environments over a 14-day period through the use of continuous glucose monitors and wrist-worn devices for the measurement of physical activity. Specifically, we will:
1.Characterise changes in glucose levels in individuals with T1D in response to everyday activities.
2.Determine whether and what activity characteristics (duration, intensity, type, and timing of activity) and personal factors are linked to individual glucose responses to activities of daily living.
REC name
London - Hampstead Research Ethics Committee
REC reference
23/PR/0500
Date of REC Opinion
3 Aug 2023
REC opinion
Further Information Favourable Opinion