Immune response to SARS-CoV-2 vaccination
Research type
Research Study
Full title
Can we characterise the immune response to SARS-CoV-2 infection and vaccination in different immunocompromised populations? Is there a correlate of protection?
IRAS ID
303982
Contact name
Anna Riddell
Contact email
Sponsor organisation
Barts Health NHS Trust
Duration of Study in the UK
0 years, 6 months, 31 days
Research summary
To investigate the immune response to SARS COV 2 and COVID vaccines in different immunocompromised patients. Our assessment would include an assessment of antibody responses (including neutralising antibody responses): following vaccination and in those patients who have an infection despite vaccination (breakthrough).
We also plan to assess cell mediated immunity by using an interferon release assay. This assesses T cell responses on stimulation with SARS CoV 2.
REC name
North of Scotland Research Ethics Committee 2
REC reference
22/NS/0032
Date of REC Opinion
16 Mar 2022
REC opinion
Unfavourable Opinion