Imaging and Vision in Glaucoma v1

• Research type

  Research Study

• Full title

  Imaging and Vision in Glaucoma

• IRAS ID

  337714

• Contact name

  Jonathan Denniss

• Contact email

  j.denniss@bradford.ac.uk

• Sponsor organisation

  University of Bradford

• Clinicaltrials.gov Identifier

  N/A, N/A

• Duration of Study in the UK

  6 years, 0 months, 0 days

• Research summary

  This project aims to improve understanding of changes to the retina and corresponding vision changes caused by glaucoma, and to take steps towards improved vision tests and eye imaging techniques useful for detection and monitoring of glaucoma.

  Study participants will be people with glaucoma and age-similar healthy volunteers. Participants will visit the School of Optometry & Vision Science on 1-8 occasions, depending on which aspects of the study they take part in. Each visit
  will last a maximum of three hours.

  Studies will involve eye and vision screening tests, identical to those performed during routine “high street” eye examinations, and new vision tests carried out on screens aiming to investigate specific aspects of vision. These tests will involve the participant viewing a screen from a fixed distance (typically maintained by placing their chin on a rest) and responding to patterns (e.g. spots, stripes, checkerboards) or images (e.g. everyday scenes) on the screen verbally or by pressing buttons. Additionally, images of the eye will be captured using existing devices routinely used
  in “high street” optometry.

  All procedures will be non-invasive, apart from the possible installation of eye drops to dilate the pupil and/or numb the front surface of the eye for eye pressure measurement. This is routinely carried out in “high street” optometry, and will
  only be carried out by qualified persons. Taking part in any of the studies will not affect participants’ clinical care in any way.

  Data will be analysed to investigate changes to vision and ocular structures attributable to glaucoma, and to develop new vision and imaging tests for glaucoma.

  We will also ask participants for permission to re-use anonymised data in future studies. This may include wider dissemination of the data, e.g. through an open-access platform. Any such dissemination of data will be strictly anonymised with no possible identifying information included.

• REC name

  South West - Frenchay Research Ethics Committee

• REC reference

  24/SW/0078

• Date of REC Opinion

  5 Sep 2024

• REC opinion

  Further Information Favourable Opinion